发明名称 |
PEPTIDES DESIGNED FOR THE DIAGNOSIS AND TREATMENT OF RHEUMATOID ARTHRITIS |
摘要 |
The present invention relates to peptides that mimic the immunogenic determinants of self-proteins recognised by autoimmune antibodies in a biological sample from patients suffering from rheumatoid arthritis (RA). More particularly, the present invention relates to citrulline-containing peptides, which react with the majority of the latter antibodies. Furthermore, the present invention relates to diagnostic tools for a more convenient and sensitive diagnosis of RA and to therapeutical methods to treat RA. |
申请公布号 |
WO0146222(A3) |
申请公布日期 |
2002.01.17 |
申请号 |
WO2000EP13037 |
申请日期 |
2000.12.20 |
申请人 |
INNOGENETICS N.V.;UNION, ANN;MOEREELS, HENRI;MEHEUS, LYDIE |
发明人 |
UNION, ANN;MOEREELS, HENRI;MEHEUS, LYDIE |
分类号 |
A61K39/00;A61P19/02;C07K7/08 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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