发明名称 |
MODULATION OF <i>IN VIVO</i> GLUTAMINE AND GLYCINE LEVELS IN THE TREATMENT OF AUTISM |
摘要 |
A method of treating autism in a patient. The method includes administering to the patient an effective amount of a glutamine level reducing agent, a glycine level reducing agent or combinations thereof. Representative glutamine level reducing agents are phenylbutyrate and phenylacetate, and a representative glycine level reducing agent is sodium benzoate. Optionally, an N-methyl-D-aspartate receptor antagonist can also be administered to the patient. A representative N-methyl-D-aspartate receptor antagonist is dextromethorphan.
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申请公布号 |
WO0141707(A3) |
申请公布日期 |
2002.01.17 |
申请号 |
WO2000US42568 |
申请日期 |
2000.12.05 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
PHILLIPS, JOHN, A., III;MCGREW, SUSAN, G. |
分类号 |
A61K31/19;A61K31/192;A61K31/485;(IPC1-7):A61K31/19;A01K31/195 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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