摘要 |
This disclosure relates to the use of alpha , alpha -dibromo- alpha -chloroacetophenone compounds as intermediates for the preparation of aromatic carbonyl compounds, especially aromatic amides. The compound 2,5-bis(2,2,2-trifluoroethoxy)- alpha , alpha -dibromo- alpha -chloro-acetophenone is especially useful as an intermediate for the preparation of flecainide, a known pharmaceutical. |
申请人 |
GENEVA PHARMACEUTICALS, INC.;RAY, ANUP, KUMAR;PATEL, HIREN, KUMAR, V.;MERAI, SHILPA, V.;PATEL, MAHENDRA, R. |
发明人 |
RAY, ANUP, KUMAR;PATEL, HIREN, KUMAR, V.;MERAI, SHILPA, V.;PATEL, MAHENDRA, R. |