METHOD FOR PRODUCING AND USING NOVEL HUMAN DEFENSINS AS BIOLOGICALLY ACTIVE PROTEINS FOR TREATING INFECTIONS AND OTHER ILLNESSES

摘要

The invention relates to novel peptides taken from human blood, hBD-5 (human beta-defensin 5), hBD-6, hBD-7, hBD-8, hBD-10, hBD-11, hBD-12, hBD-13, hBD-14, hBD-15, hBD-16, hBD-17, hBD-18, hBD-19, hBD-20, hBD-22, hBD-23, hBD-24, hBD-25, hBD-26, hBD-27, hBD-28, hBD-29, hBD-30, hBD-31 and hBD-32 and the derivatives thereof, the structure of the same having been elucidated so that they can be used therapeutically, diagnostically and commercially as medicaments. Said peptides can be produced by means of biotechnological, recombinant methods and chemical synthesis, and can be proteolytically derived from corresponding precursor proteins.