| 发明名称 |
METHOD FOR LOCALIZED ADMINISTRATION OF FIBRINOLYTIC METALLOPROTEINASES |
| 摘要 |
A method is provided for the localized intravascular administration of a fibrinolytic metalloproteinase to a human subject in amounts that are both safe and effective to lyse an occluding fibrin-containing blood clot, while also avoiding the neutralizing effects of alpha 2-macroglobulin in the circulating blood.
|
| 申请公布号 |
WO0143765(A3) |
申请公布日期 |
2002.01.17 |
| 申请号 |
WO2000US34143 |
申请日期 |
2000.12.15 |
| 申请人 |
AMGEN INC. |
发明人 |
TOOMBS, CHRISTOPHER, FRANCIS |
| 分类号 |
A61K9/08;A61K38/12;A61K38/46;A61K38/48;A61P7/02;A61P9/00;(IPC1-7):A61K38/48;A61P9/10 |
主分类号 |
A61K9/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
