发明名称 CHIRAL INTEGRIN MODULATORS AND METHODS OF USE THEREOF
摘要 The invention provides enantiomers of ajoene and derivtives of Z(-)-ajoene. The derivative of Z(-)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.
申请公布号 CA2415985(A1) 申请公布日期 2002.01.17
申请号 CA20012415985 申请日期 2001.07.10
申请人 BILINGS PHARMACEUTICALS, INC. 发明人 HILDRETH, JAMES E. K.;DAVIDSON, JOHN B.;TURGIEV, ALI S.;TATARINTSEV, ALEXANDER V.
分类号 C07C323/65;(IPC1-7):C07C321/12;C07C321/18 主分类号 C07C323/65
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