| 摘要 |
<p>The present invention relates to fatty acid analogues of general formula (I): R1- [xi - CH2]n - COOR2, wherein R1 is: a C1-C24 alkene with one or more double bonds and/or with one or more triple bonds; and/or a C1-C24 alkyne, and/or a C1-C24 alkyl, or an alkyl substituted in one or several positions with one or more compounds selected from the group comprising fluoride, chloride, hydroxy, C1-C4 alkoxy, C1-C4 alkylthio, C2-C5 acyloxy or C1-C4 alkyl, and wherein R2 represents hydrogen or C1-C4 alkyl, and wherein n is an integer from 1 to 12, and wherein i is an odd number and indicates the position relative to COOR2, and wherein Xi independent of each other are selected from the group comprising O, S, SO, SO2, Se and CH2, and with the proviso that at least one of the Xi is not CH2, which can be used for the treatment and/or prevention of primary and secondary metastatic neoplasms.</p> |
