发明名称 |
METHOD FOR DETERMINING THREE-DIMENSIONAL PROTEIN STRUCTURE FROM PRIMARY PROTEIN SEQUENCE |
摘要 |
A preferred embodiment of the invention is a method for determining a preferred sequence alignment between a query sequence and one or more templa te sequences comprising the steps of: 1) aligning at least two reference sequences to determine one or more BRIDGE/BULGE gaps; 2) determining an alignment score between each potential alignment of the query sequence and each template sequence based on whether or not a given sequence alignment between the query sequence and each template sequence creates a BRIDGE/BULGE gap and 3) determining a preferred sequence alignment based on the alignment scores of the query sequence with each template sequence.
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申请公布号 |
CA2415787(A1) |
申请公布日期 |
2002.01.17 |
申请号 |
CA20012415787 |
申请日期 |
2001.07.12 |
申请人 |
CALIFORNIA INSTITUTE OF TECHNOLOGY |
发明人 |
DEBE, DEREK A. |
分类号 |
G01N33/48;C07K14/00;G01N33/15;G01N33/68;G06F17/15;G06F17/30;G06F19/16;G06F19/22;(IPC1-7):G01N33/68;G06F17/00;G01N31/00;G01N33/53;C12Q1/68 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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