发明名称 Process for preparing R- a S- isomers of 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide
摘要 <p>In the present invention there is disclosed a process for preparing optically pure enantiomers of R-(-)tamsulosin of the general formula (Ia) and S-(+)tamsulosin of the general formula (Ib) by splitting a racemic tamsulosin of the general formula (I) by treatment thereof with the (1R)-(-)-camphor-10-sulfonic, respectively (1S)-(+)-camphor-10-sulfonic acid in the medium of organic solvents, water or mixtures thereof.</p>
申请公布号 CZ20012077(A3) 申请公布日期 2002.01.16
申请号 CZ20010002077 申请日期 2001.06.08
申请人 FARMAK, A.S. 发明人 HRADIL PAVEL DOC. ING. CSC.;URBASEK MIROSLAV ING.;KVAPIL LUBOMIR RNDR.;SLEZAR PETR ING.
分类号 C07C303/44;C07B57/00;C07C311/39;(IPC1-7):C07C303/44 主分类号 C07C303/44
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