发明名称 |
Process for preparing R- a S- isomers of 5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzene sulfonamide |
摘要 |
<p>In the present invention there is disclosed a process for preparing optically pure enantiomers of R-(-)tamsulosin of the general formula (Ia) and S-(+)tamsulosin of the general formula (Ib) by splitting a racemic tamsulosin of the general formula (I) by treatment thereof with the (1R)-(-)-camphor-10-sulfonic, respectively (1S)-(+)-camphor-10-sulfonic acid in the medium of organic solvents, water or mixtures thereof.</p> |
申请公布号 |
CZ20012077(A3) |
申请公布日期 |
2002.01.16 |
申请号 |
CZ20010002077 |
申请日期 |
2001.06.08 |
申请人 |
FARMAK, A.S. |
发明人 |
HRADIL PAVEL DOC. ING. CSC.;URBASEK MIROSLAV ING.;KVAPIL LUBOMIR RNDR.;SLEZAR PETR ING. |
分类号 |
C07C303/44;C07B57/00;C07C311/39;(IPC1-7):C07C303/44 |
主分类号 |
C07C303/44 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|