| 摘要 |
PURPOSE: Provided is a method for producing nucleotides by fermentation. Nucleotides such as nucleoside 5'-phosphate esters are useful as seasonings, drugs, raw materials thereof and so forth. CONSTITUTION: A method for producing nucleoside 5'-phosphate ester, comprises the steps of culturing a bacterium belonging to the genus Escherichia having an ability to produce nucleoside 5'-phosphate ester, in which ushA gene and aphA gene do not function normally, in a medium to produce and accumulate nucleoside 5'-phosphate ester in the medium. |
