发明名称 Process for preparing doxazosin mesylate in crystalline modification designated as form A
摘要 <p>The invention relates to a method for producing doxazosin mesylate in the modification A. The method is characterised in that doxazosin and methane sulphonic acid are dissolved in a mixture containing an aprotic, polar organic solvent and methanol. Any clouding in the resulting solution is optionally eliminated. The clear solution thus produced is optionally injected with doxazosin mesylate crystals of form A, heated and isolated after the resulting product has been cooled. Said product is then washed with an organic solvent and dried.</p>
申请公布号 CZ20013347(A3) 申请公布日期 2002.01.16
申请号 CZ20010003347 申请日期 2000.03.06
申请人 KNOLL AKTIENGESELLSCHAFT 发明人 KLEIN PETER;THYES MARCO
分类号 A61K31/517;A61P9/12;C07D405/12;(IPC1-7):C07D405/14 主分类号 A61K31/517
代理机构 代理人
主权项
地址