发明名称 INHIBITORS OF UROKINASE AND BLOOD VESSEL FORMATION
摘要 Novel inhibitors of urokinase are provided which have an arginine or arginine mimic aldehyde or an arginine ketoamide group at P1. These compounds are useful in vitro for monitoring plasminogen activator levels and in vivo in treatment of conditions which are ameliorated by inhibition of or decreased activity of urokinase.
申请公布号 PL345960(A1) 申请公布日期 2002.01.14
申请号 PL19990345960 申请日期 1999.07.22
申请人 CORVAS INTERNATIONAL,INC. 发明人 BRUNCK TERENCE K.;TAMURA SUSAN Y.
分类号 C12N9/99;A61K38/00;A61P9/10;A61P17/06;A61P17/12;A61P19/08;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P35/04;A61P43/00;C07K5/06;C07K5/068;C07K5/08;(IPC1-7):C07K5/062;A61K38/04 主分类号 C12N9/99
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