发明名称 |
Structure-based hepatitis c virus drug design |
摘要 |
The extracellular loop of CD81 is a cellular receptor for the E2 protein of hepatitis C virus. A CD81 crystal structure has been elucidated and is provided for use in the structure-based design of compounds which bind to CD81 and thus block the binding of HCV. Methods such as docking and de novodrug design can be used. |
申请公布号 |
AU7662301(A) |
申请公布日期 |
2002.01.14 |
申请号 |
AU20010076623 |
申请日期 |
2001.07.03 |
申请人 |
CHIRON S.P.A. |
发明人 |
MARTINO BOLOGNESI;GUIDO GRANDI |
分类号 |
C07K14/705;G01N33/576;G01N33/68;G06F19/16 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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