发明名称 Inhibitors of prenyl-protein transferase
摘要 The present invention is directed to macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras.
申请公布号 AU7301001(A) 申请公布日期 2002.01.14
申请号 AU20010073010 申请日期 2001.06.26
申请人 MERCK AND CO., INC. 发明人 THERESA M. WILLIAMS;CRAIG A. STUMP
分类号 C07D498/22 主分类号 C07D498/22
代理机构 代理人
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