发明名称 |
Substituted-triazolopyrimidines as anticancer agents |
摘要 |
The invention provides a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof which comprises administering to said mammal an effective amount of a substituted triazolopyrimidine derivative or a pharmaceutically acceptable salt thereof and further provides a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by interacting with tubulin and microtubules and promoting microtubule polymerization which comprises administering to said mammal an effective amount of a substituted triazolopyrimidine derivative or a pharmaceutically acceptable salt thereof. |
申请公布号 |
AU7306201(A) |
申请公布日期 |
2002.01.14 |
申请号 |
AU20010073062 |
申请日期 |
2001.06.28 |
申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
MARK R SCHMITT;DONALD R. KIRSCH;JANE E. HARRIS;CARL F. BEYER;KLAUS-JUERGEN PEES;PAUL CARTER;WALDEMAR PFRENGLE;GUIDO ALBERT |
分类号 |
A61K31/519;A61K31/541;A61K31/55;A61P35/00;A61P35/04;A61P43/00;C07D487/04;C07D519/00 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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