摘要 |
<p>A method of screening a drug by using a disease-associated gene product; an antibody against the disease-associated gene product; an antisense DNA inhibiting the expression of the disease-associated gene, etc. A compound regulating the activity of a protein having an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:1 or its salt, a neutralizing antibody regulating the activity of the above protein, an antisense DNA, etc. can regulate the expression of the protein having an amino acid sequence which is the same or substantially the same as the amino acid sequence represented by SEQ ID NO:1 and, therefore, are usable as preventives and remedies for diseases such as heart diseases.</p> |