METHOD FOR SCREENING MCH RECEPTOR ANTAGONIST/AGONIST

摘要

A method for screening compounds or salts thereof which change the affinity of MCH or a salt thereof with SLT or a salt thereof, or its peptide fragment or its amide or its ester or its salt, characterized in that it comprises using MCH or a derivative thereof or its salt, and SLT or a salt thereof or its peptide fragment or its amide or its ester or its salt. The method is useful as a method for screening SLT agonists which can be used as an appetite stimulating agent and the like, and SLT antagonists which can be used as a preventive/ therapeutic agent for obesity and the like.