| 发明名称 |
4-HETEROARYL-3-HETEROARYLIDENYL-2-INDOLINONES AND THEIR USE AS PROTEIN KINASE INHIBITORS |
| 摘要 |
The present invention relates to certain 4-heteroaryl-3-heteroarylidenyl-2- idolinones compounds and their physiologically acceptable salts which modula te the activity of protein kinases ("PKs"), in particular CDK2. The compounds o f the present invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical composition containing these compounds and methods of preparing these compounds are also described.
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| 申请公布号 |
CA2414468(A1) |
申请公布日期 |
2002.01.10 |
| 申请号 |
CA20012414468 |
申请日期 |
2001.06.29 |
| 申请人 |
SUGEN, INC. |
发明人 |
CUI, JINGRON;TANG, PENG CHO;WEI, CHUNG CHEN;HUANG, PING |
| 分类号 |
C07D491/052;A61K31/4439;A61K31/4545;A61K31/496;A61K31/506;A61K31/5377;A61P3/10;A61P9/10;A61P17/06;A61P19/02;A61P25/28;A61P29/00;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07D401/04;C07D401/14;C07D403/06;C07D403/14;C07D409/14;C07D417/14;C07D471/04;C07D491/04;(IPC1-7):C07D401/14;C07D207/00;C07D209/00;C07D213/00;C07D233/00;A61K31/40 |
主分类号 |
C07D491/052 |
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