发明名称 BICYCLIC AND TRICYCLIC HETEROAROMATIC COMPOUNDS
摘要 Disclosed are compounds of formula (I) and the pharmaceutically acceptable salts thereof, wherein W, Q, X, X1, Y and Z are as defined herein. These compounds bind with high selectivity and/or high affinity to the benzodiazepine site of GABAA receptors and re therefore useful in the treatment of central nervous system (CNS) diseases and as probes for the localization of GABAA receptors in tissue samples. Also disclosed are intermediates useful in the preparation of these compounds.
申请公布号 WO0134603(A3) 申请公布日期 2002.01.10
申请号 WO2000US30905 申请日期 2000.11.10
申请人 NEUROGEN CORPORATION;YUAN, JUN;ALBAUGH, PAMELA;SHAW, KENNETH;HUTCHISON, ALAN 发明人 YUAN, JUN;ALBAUGH, PAMELA;SHAW, KENNETH;HUTCHISON, ALAN
分类号 A61K31/437;A61K31/4545;A61K31/496;A61K31/5377;A61K31/541;A61K31/55;A61P25/00;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D217/26;C07D237/30;C07D471/04;C07D487/04;C07D519/00;(IPC1-7):C07D471/04;A61K31/502;G01N33/566 主分类号 A61K31/437
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