| 摘要 |
Described are polynucleotide encoding TZON7 protein or a biologically fragment thereof. Furthermore, vectors are described comprising said polynucleotides and/or host cells transformed therewith. Additionally, antisense constructs to said polynucleotides are described. Furthermore, methods and uses for modulating immune responses through the TZON7 protein as well as pharmaceutical compositions comprising agents which act on the TZON7 protein are described. Also, the use of said polynucleotides, vectors, proteins or antibodies for the preparation of diagnostic and pharmaceutical compositions for use, inter alia, in organ transplantation, for the treatment of autoimmune, allergic or infectious diseases, or for treatment of tumors is provided.
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