发明名称 |
NOVEL MOLECULES AND THE CARD-RELATED PROTEIN FAMILY AND USES THEREOF |
摘要 |
Novel CARD-12 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-12 proteins, the invention further provides CARD-12, fusion proteins, antigenic peptides and anti-CARD-12 antibodies. The invention also provides CARD-12 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CARD-12 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the inventions are also provided.
|
申请公布号 |
WO0130971(A3) |
申请公布日期 |
2002.01.10 |
申请号 |
WO2000US29643 |
申请日期 |
2000.10.26 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;BERTIN, JOHN;ROBISON, KEITH, E. |
发明人 |
BERTIN, JOHN;ROBISON, KEITH, E. |
分类号 |
A61K38/00;C07K14/47;(IPC1-7):C07K14/47;C07K7/08;C07K16/18;C12N1/00;C12N5/00;C12N5/06;C12N15/12;C12P21/02;C12Q1/37;C12Q1/68;G01N33/53;G01N33/566;G01N33/68 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|