MELANIN COAGULATING HORMONE ANTAGONISTIC AGENT

摘要

PROBLEM TO BE SOLVED: To provide a melanin coagulating hormone antagonist useful for the prevention and treatment of obesity. SOLUTION: This melanin coagulating hormone antagonist contains a compound of the formula [Ar1 is a (substituted)cyclic group; X is a spacer having a main chain containing 1-6 atoms; Y is a bond or a spacer having a main chain containing 1-6 atoms; Ar is a (substituted)monocyclic aromatic ring which may be condensed with a 4 to 8-membered non-aromatic ring; and R1 and R2 are each independently hydrogen atom or a (substituted)hydrocarbon group, R1 and R2 may together with adjacent nitrogen atom form a (substituted) nitrogen-containing heterocyclic group or R2 may together with Ar form a spiro ring or together with adjacent nitrogen atom and Y form a (substituted) nitrogen-containing heterocyclic group].