| 摘要 |
This invention is a liver support apparatus for treating a patient with a liver disease. The apparatus comprises a containment chamber (100) containing a disposable diaphragm (140). The diaphragm is configured to hold the liver and is oscillated intermittently in a manner that replicates the respirator movement of the liver in vivo. The chamber is connected to a ventilator (16) by an air hose (18). Air pressure from the ventilator into the chamber causes the diaphragm to oscillate in a fashion that mimics the movement of the liver in vivo. The apparatus also comprises cannulae (22, 25, 26, 34) that pass through ports in the chamber; openings in the diaphragm that are inserted in one end in the liver's hepatic artery, and the portal vein; and at the other end in the hepatic vein. Arterial whole blood is passed through the cannulae of the hepatic artery, the portal vein, and out of the hepatic vein cannula, thereby completely perfusing the liver. |
