发明名称 Compositions and methods for protein secretion
摘要 The present invention relates to compositions and methods for secretion of functional proteins in a soluble form by host cells. In particular, the invention relates to membrane targeting and translocation proteins, MttA, MttB and MttC and to variants and homologs thereof. The membrane targeting and translocation proteins are useful in targeting protein expression to the periplasm of gram negative bacteria and to extracellular media of other host cells. Such expression allows secretion of expressed proteins of interest in a functional and soluble form, thus facilitating purification and increasing the yield of functional proteins of interest.
申请公布号 US6335178(B1) 申请公布日期 2002.01.01
申请号 US19980085761 申请日期 1998.05.28
申请人 UNIVERSITY OF ALBERTA 发明人 WEINER JOEL HIRSCH;TURNER RAYMOND JOSEPH
分类号 C07K14/245;C12N15/62;C12N15/63;(IPC1-7):C12P21/06;C12N1/20;C07K14/00;C07H21/04 主分类号 C07K14/245
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