发明名称 |
5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST |
摘要 |
<p>Compounds of formula (I), wherein Q<1>, Q<2>, Q<3> and Q<4> have any of the meanings given in the specification, their N-oxided, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA, useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula (I) and intermediates.</p> |
申请公布号 |
GR3036639(T3) |
申请公布日期 |
2001.12.31 |
申请号 |
GR20010401497T |
申请日期 |
2001.09.18 |
申请人 |
ZENECA LIMITED |
发明人 |
BERNSTEIN, PETER, ROBERT;DEMBOFSKY, BRUCE, THOMAS;JACOBS, ROBERT, TOMS |
分类号 |
A61K31/4427;A61K31/445;A61K31/4468;A61K31/451;A61K31/47;A61P11/00;C07D211/52;C07D211/58;C07D401/04;C07D401/06;C07D401/12;C07D405/12;C07D409/12;C07D413/04;C07D417/04;C07D471/10;(IPC1-7):C07D211/52 |
主分类号 |
A61K31/4427 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|