| 发明名称 |
METHOD OF CONTROLLING DIFFERENTIATION OF EMBRYONIC STEM (ES)CELLS BY CULTURING ES CELLS IN THE PRESENCE OF BMP-2 PATHWAY ANTAGONISTS |
| 摘要 |
<p>ES cells have a natural tendency to differentiate into cells resembling thos e of the extra-embryonic endodermal lineages in the early human embryo. Applicants have found that culturing ES cells in the presence of direct and/ or indirect antagonists of the BMP-mediated default pathway of extra-embryonic endoderm differentiation will prevent ES cells from proceeding along this pathway.</p> |
| 申请公布号 |
CA2411914(A1) |
申请公布日期 |
2001.12.27 |
| 申请号 |
CA20012411914 |
申请日期 |
2001.06.20 |
| 申请人 |
ES CELL INTERNATIONAL PTE LTD |
发明人 |
PERA, MARTIN FREDERICK |
| 分类号 |
C12N5/0735;(IPC1-7):C12N5/08 |
主分类号 |
C12N5/0735 |
| 代理机构 |
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