摘要 |
A class of styryl amidine derivatives which are antagonists of the hum NMDA receptor, being selective for those containing the NR2B subunit, are active in the treatment and/or prevention of neurological and neurodegenerative disorders, in particular neuropathic pain and headache, specifically migraine, whils displaying fewer ataxic and related side-effects associated with other classes of NMDA receptor antagonists.
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申请人 |
MERCK SHARP & DOHME LIMITED;CURTIS, NEIL, ROY;KULAGOWSKI, JANUSZ, JOZEF;THOMAS, STEVE;WATT, ALAN, PAUL |
发明人 |
CURTIS, NEIL, ROY;KULAGOWSKI, JANUSZ, JOZEF;THOMAS, STEVE;WATT, ALAN, PAUL |