发明名称 |
NOVEL NON-PSYCHOTROPIC CANNABINOIDS |
摘要 |
Novel non-psychotropic cannabinoids are disclosed and pharmaceutical compositions comprising these novel compounds are described for preventing neurotoxicity, neuroinflammation, immune or inflammatory disorders comprising as active ingredient the stereospecific (+) enantiomer, having (3S, 4S) configuration of DELTA <6> tetrahydrocannabinol type compounds. The compositions are particularly effective in alleviating and even preventing neurotoxicity due to acute injuries to the central nervous system, including mechanical trauma, compromised or reduced blood supply as may occur in cardiac arrest or stroke, or poisonings. They are also effective in the treatment of certain inflammatory disorders and chronic degenerative diseases characterized by neuronal loss and chronic pain including neuropathic pain.
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申请公布号 |
WO0198289(A1) |
申请公布日期 |
2001.12.27 |
申请号 |
WO2001IL00571 |
申请日期 |
2001.06.22 |
申请人 |
PHARMOS CORPORATION;GARZON, AARON;FINK, GEORGE |
发明人 |
GARZON, AARON;FINK, GEORGE |
分类号 |
A61K31/352;A61K31/381;A61K31/4025;A61K31/4155;A61K31/4178;A61K31/4196;A61K31/4433;A61K31/453;A61K31/454;A61K31/4545;A61K31/496;A61K31/5377;A61P1/04;A61P1/08;A61P1/16;A61P5/14;A61P7/10;A61P9/00;A61P9/10;A61P11/00;A61P13/12;A61P17/02;A61P19/02;A61P19/08;A61P25/00;A61P25/04;A61P25/08;A61P25/16;A61P25/18;A61P25/28;A61P27/00;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P37/06;A61P39/02;A61P43/00;C07D311/80;C07D405/06;C07D405/12;C07D409/06;C07D521/00;(IPC1-7):C07D311/80;C07D233/02;A61K31/35;A61K31/415 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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地址 |
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