| 摘要 |
Subject of the invention are collagen hemostatic pellets containing collagen gel in the contacting surface. The hemostatic pellets preferably contain physiologically active substances as additives. They either are based on a homogeneous collagen composition, or comprise collagen gel as a layer. The further subject of the invention is the method of producing the collagen hemostatic pellets by dissolving a collagen source at an acid pH, optionally neutralizing the collagen solution to produce a gel at pH 6-8, and pelleting the gel by centrifugation, spray-drying, fluid-bed drying and/or encapsulating. The collagen hemostatic pellets according to the invention can be used in various surgical interventions, in particular for laparoscopic procedures. |
