| 摘要 |
PROBLEM TO BE SOLVED: To obtain a compound or a benzisoxazole derivative having activating actions on a peroxisome proliferator activated receptorδ(PPARδ). SOLUTION: This benzisoxazole derivative represented by the general formula (II), wherein A denotes O, S or the like; R1, R2 and R3 denote each hydrogen atom, a 1-8C alkyl group, phenyl group or the like which may have a substituent group; X1 and X2 denote each O, S, a direct bond or the like; Y1 denotes a 1-8C alkylene chain which may have a substituent group; Z denotes O or S; and R4 and R5 denote each hydrogen atom, a 1-8C alkyl or the like or its salt is used as an activator for the PPARδ.
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