METHOD FOR OPTICAL RESOLUTION OF PIPERIDINECARBOXYLIC ACID DERIVATIVE

摘要

PROBLEM TO BE SOLVED: To provide a method for producing an optically active piperidinecarboxylic acid derivative useful as an intermediate for pharmaceuticals in high yield and purity. SOLUTION: An optically active piperidinecarboxylic acid derivative is produced by treating a piperidinecarboxylic acid derivative of formula (1) (Z is a protecting group for carboxylic acid) with an optical resolution agent of formula (2) (the carbon atom marked with asterisk is asymmetric carbon atom).