PROCESS AND INTERMEDIATES FOR THE PREPARATION OF SPIRO[ISOQUINOLINE-4(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONES WHICH ARE USEFUL AS ALDOSE REDUCTASE INHIBITORS

摘要

This invention relates to a process for producing spiro-isoquinoline- pyrrolidines. The compounds have pharmaceutical properties which render them beneficial for the prevention or treatment of diabetes mellitus associated complications.