| 摘要 |
Carboxylic acids of formula (1):wherein R2 and R3 are independently hydrogen or C1-C3 alkyl, and Q is optionally substituted phenyl, can be easily converted by ring closing into pyridazin-3-one derivatives of formula (7):The carboxylic acids of formula (1) can be produced by reacting hydrazone compounds of formula (5):wherein R3 and Q are as defined above, with malonic acid derivatives of formula (6):wherein R2 is as defined above, in the presence of a base.
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