发明名称 |
3'-prodrugs of 2'-deoxy-beta-L-nucleosides |
摘要 |
The present invention relates to compounds, compositions and methods for the treatment of a host infected with a hepatitis B virus. Specifically, compounds and compositions of 3'-esters of 2'-deoxy- beta -L-nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents. Compounds and compositions of 3',5'-esters of 2'-deoxy-ss-L-nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents, are also disclosed. |
申请公布号 |
AU6692701(A) |
申请公布日期 |
2001.12.24 |
申请号 |
AU20010066927 |
申请日期 |
2001.06.15 |
申请人 |
NOVIRIO PHARMACEUTICALS LIMITED;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
MARTIN L BRYANT;GILLES GOSSELIN;JEAN-LOUIS IMBACH |
分类号 |
C07D239/47;A61K31/513;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/708;A61K45/00;A61P31/12;A61P31/20;A61P43/00;C07H19/06;C07H19/073;C07H19/16;C07H19/173 |
主分类号 |
C07D239/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|