| 摘要 |
The invention provides isolated nucleic acid molecules, designated CONAT-1 nucleic acid molecules, which encode novel acetyltransferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CONAT-1 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a CONAT-1 gene has been introduced or disrupted. The invention still further provides isolated CONAT-1 proteins, fusion proteins, antigenic peptides and anti-CONAT-1 antibodies. Diagnostic methods utilizing compositions of the invention are also provided. |
