发明名称 |
Use of an aldosterone antagonist for the treatment or prohpylaxis of aldosterone-mediated pathogenic effects |
摘要 |
The present invention provides methods for the treatment or porphylaxis of one or more aldosterone-mediated pathogenic effects in a subject suffering from or susceptible to the pathogenic effect or effects wherein the subject has one or more conditions selected from the group consisting of a sub-normal endogenous aldosterone level, salt sensitivity and an elevated dietary sodium intake. The methods comprise administering to the subject a therapeutically-effective amount of one or more epoxy-steroidal compounds that are aldosterone antagonists. |
申请公布号 |
AU1604001(A) |
申请公布日期 |
2001.12.24 |
申请号 |
AU20010016040 |
申请日期 |
2000.11.01 |
申请人 |
PHARMACIA CORPORATION |
发明人 |
GORDON H. WILLIAMS;JOHN W. FUNDER;SUSAN M. GARTHWAITE;BARBARA RONIKER;KENTON N. FEDDE;RICARDO ROCHA |
分类号 |
A61K45/00;A61K31/00;A61K31/415;A61K31/4152;A61K31/437;A61K31/5513;A61K31/56;A61K31/57;A61K31/58;A61K31/585;A61K45/06;A61P1/16;A61P3/10;A61P7/10;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P13/12;A61P15/08;A61P25/00;A61P25/06;A61P27/02;A61P43/00;C07J9/00 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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