发明名称 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
摘要 Provided are compounds of general formula (I), wherein R<2> is selected from the group consisting of H, F, Cl, (C1-4) alkyl, (C3-4) cycloalkyl and CF3; R<4> is H or Me; R<5> is H, Me or Et, with the proviso that R<4> and R<5> are not both Me, and if R<4> is Me then R<5> cannot be Et; R<11> is Et, cyclopropyl, propyl, isopropyl, or isobutyl; and Q is selected from the group consisting of (II), (III), (IV) and (V); and pharmaceutically acceptable salts thereof, as inhibitors of HIV reverse transcriptase, wild-type and several mutant strains.
申请公布号 WO0196338(A1) 申请公布日期 2001.12.20
申请号 WO2001CA00890 申请日期 2001.06.14
申请人 BOEHRINGER INGELHEIM (CANADA) LTD.;SIMONEAU, BRUNO 发明人 SIMONEAU, BRUNO
分类号 A61K;A61K31/55;A61K31/551;A61P31/18;A61P43/00;C07D;C07D471/14;(IPC1-7):C07D471/14 主分类号 A61K
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