| 发明名称 |
CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS |
| 摘要 |
The present invention relates compounds of formula (I), wherein ring A is a phenyl or pyridyl ring; X represents a linker selected from the group consisting of formulae: (a), (b), (c), (d), and (e); and R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<13>, R<14>, R<15>, R<16>, R<17>, R<21a> and R<21b> are as defined herein. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
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| 申请公布号 |
WO0187838(A8) |
申请公布日期 |
2001.12.20 |
| 申请号 |
WO2001GB02145 |
申请日期 |
2001.05.16 |
| 申请人 |
MERCK SHARP & DOHME LIMITED;CASTRO PINEIRO, JOSE, LUIS;DINNELL, KEVIN;ELLIOTT, JASON, MATTHEW;HOLLINGWORTH, GREGORY, JOHN;SHAW, DUNCAN, EDWARD;SWAIN, CHRISTOPHER, JOHN |
发明人 |
CASTRO PINEIRO, JOSE, LUIS;DINNELL, KEVIN;ELLIOTT, JASON, MATTHEW;HOLLINGWORTH, GREGORY, JOHN;SHAW, DUNCAN, EDWARD;SWAIN, CHRISTOPHER, JOHN |
| 分类号 |
C07D295/12;A61K31/165;A61K31/167;A61K31/196;A61K31/223;A61K31/27;A61K31/357;A61K31/40;A61K31/421;A61K31/4355;A61K31/438;A61K31/439;A61K31/444;A61K31/451;A61K31/472;A61K31/495;A61K31/496;A61K31/4985;A61K31/506;A61K31/5375;A61K31/541;A61K31/55;A61P1/08;A61P25/04;A61P25/06;A61P25/22;A61P25/24;A61P29/00;A61P43/00;C07C233/11;C07C233/23;C07C233/32;C07C233/41;C07C237/04;C07C237/06;C07C271/20;C07C271/22;C07C271/24;C07C309/66;C07D207/06;C07D207/08;C07D211/14;C07D211/18;C07D211/22;C07D211/38;C07D211/42;C07D211/44;C07D211/46;C07D211/48;C07D211/58;C07D211/60;C07D211/62;C07D211/74;C07D217/04;C07D241/08;C07D263/22;C07D265/30;C07D275/04;C07D295/135;C07D309/14;C07D317/72;C07D401/04;C07D403/04;C07D403/06;C07D405/04;C07D407/04;C07D417/04;C07D453/06;C07D471/10;C07D487/04;C07D491/048;C07D491/107;C07D491/113;(IPC1-7):C07D211/58;A61K31/440;A61K31/164;A61K31/435;C07C233/31;C07C237/10 |
主分类号 |
C07D295/12 |
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