PROTOBERBERINE DERIVATIVES WHICH INHIBIT ACTIVITY OF THE MITOGEN-ACTIVATED PROTEIN KINASE
摘要
The present invention relates to protoberberine derivatives which inhibit the activity of mitogen-activated protein kinase. More specifically, the present invention is directed to protoberberine derivatives which inhibit the activity of Wis1 and Spc1 kinase in intracellular signal transduction cascade wherein mitogen-activated protein kinase (MAPK) is involved.
申请公布号
WO0195908(A1)
申请公布日期
2001.12.20
申请号
WO2001KR01025
申请日期
2001.06.14
申请人
HANWHA CHEMICAL CORPORATION;SONG, KI-WON;JWA, MI-RI;JANG, MYOUNG-JIN;PAIK, YOUNG-KI;KIM, JUNG-HO