INDOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS

摘要

The present invention relates to dopamine and serotonin receptor ligands having the general formula (I) wherein one of Y<1> and Y<2> is N, which is bound to Y<4>, Y<3> is Z-CH2, CH2-Z or CH2CH2 and the further meanings of Y<1>, Y<2>, Y<3>, Y<4>, Z, W, n, m, X, R<1>-R<9> and R<10> are as given in the claims and the description. The compounds of the invention are useful in the treatment of certain psychiatric and neurological disorders, i.e. schizophrenia, other psychoses, anxiety disorders, depression, migraine, cognitive disorders, ADHD and sleep improvement.