| 发明名称 |
CARDIAC-CELL SPECIFIC ENHANCER ELEMENTS AND USES THEREOF |
| 摘要 |
The invention features cardiac cell-specific enhancer elements derived from Csx/Nkx2.5 regulatory regions. These enhancer elements are useful, for example, for (i) regulating gene expression in cardiac cells, (ii) inducing stem cells (e.g., embryonic stem cells or bone marrow stem cells) to differentiate as cardiomyocytes, and (iii) identifying factors that induce the differentiation of stem cells as cardiomyocytes.
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| 申请公布号 |
WO0151006(A3) |
申请公布日期 |
2001.12.20 |
| 申请号 |
WO2001US01511 |
申请日期 |
2001.01.16 |
| 申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER |
发明人 |
LEE, IKE, W.;IZUMO, SEIGO |
| 分类号 |
G01N33/48;A61K48/00;C07K14/47;C12N5/10;C12N15/09;C12N15/85;C12Q1/02;G01N33/15;G01N33/50;(IPC1-7):C07H21/04;C12N5/00;C12N15/12;C12N15/63;C12Q1/68 |
主分类号 |
G01N33/48 |
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