A METHOD FOR DETECTING A LIPOPROTEIN-ACUTE PHASE PROTEIN COMPLEX AND PREDICTING AN INCREASED RISK OF SYSTEM FAILURE OR MORTALITY

摘要

A method for diagnosing a condition of a patient involves the steps of (a) adding one or more reagents to a test sample from a patient, the test sample s comprising at least part of a blood sample from the patient, in order to cau se formation of a complex comprising at least one acute phase protein at at lea st one human lipoprotein, while causing substantially no fiber polymerization; (b) measuring the formation of the complex over time so as to derive a time- dependent measurement profile, and (c) determining a slope and/or total chan ge in the time-dependent measurement profile, so as to diagnose a condition of the patient. A greater formation of the complex is correlated to increased probability of death of the patient.