| 发明名称 |
EXPRESSION OF ACTIVE HUMAN PROTEIN C IN MAMMARY TISSUE OF TRANSGENIC ANIMALS |
| 摘要 |
<p>Recombinant protein C characterized by a high percentage of active protein can be obtained in the milk of transgenic mammals that incorporate DNAs according to the present invention. Transgenic mammals of the present invention are produced by introducing into developing embryos DNA that encodes protein C, such that the DNA is stably incorporated in the DNA of germ line cells of the mature mammals and inherited in normal, mendelian fashion.</p> |
| 申请公布号 |
EP0591219(B1) |
申请公布日期 |
2001.12.19 |
| 申请号 |
EP19920904523 |
申请日期 |
1992.01.07 |
| 申请人 |
AMERICAN RED CROSS;VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. |
发明人 |
DROHAN, WILLIAM N.;WILKINS, TRACY D.;VELANDER, WILLIAM H.;JOHNSON, JOHN L. |
| 分类号 |
A01K67/027;C12N9/64;C12N15/57;C12N15/85;(IPC1-7):C12N15/57 |
主分类号 |
A01K67/027 |
| 代理机构 |
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