REDUCTION OF LIPOSOME-INDUCED ADVERSE PHYSIOLOGICAL REACTIONS
摘要
<p>Provided herein is a method of administering a liposome composition to an animal, the method involving administering to the animal a liposome composition containing an adverse physiological reaction-reducing effective amount of a liposome which has, in addition to a bioactive agent, a lipid bilayer containing a lipid and a surface agent-modified molecule. An adverse physiological reaction which may be experienced by the animal upon administration of a liposome composition is reduced by way of the presence of the surface agent-modified molecule in the liposome's lipid bilayer.</p>
申请公布号
EP0699068(B1)
申请公布日期
2001.12.19
申请号
EP19940918106
申请日期
1994.05.20
申请人
THE LIPOSOME COMPANY, INC.
发明人
AHL, PATRICK, L.;BHATIA, SURESH, K.;MINCHEY, SHARMA, R.;JANOFF, ANDREW, S.