发明名称 Bismuth compounds for the treatment and prevention of mucositis
摘要 The invention relates to the unexpected discovery that bismuth-containing compounds are effective in the treatment of oral mucositis in a mammal. Thus, the invention relates, in one aspect to a method of treating oral mucositis comprising administering an effective amount of a pharmaceutically acceptable bismuth-containing compound, such as a bismuth salt or bismuth complex. In a preferred embodiment, the bismuth compound is an organic or inorganic salt such as, bismuth subsalicylate, bismuth subgallate, bismuth aluminate, bismuth citrate, bismuth subcitrate, bismuth carbonate, bismuth subcarbonate, tripotassium dicitrato bismuthate, bismuth nitrate, bismuth subnitrate, bismuth tartrate and mixtures thereof, preferably, bismuth subsalicylate and bismuth subgallate.
申请公布号 AU7545001(A) 申请公布日期 2001.12.17
申请号 AU20010075450 申请日期 2001.06.08
申请人 GELTEX PHARMACEUTICALS, INC.;FITZPATRICK, RICHARD, J. 发明人 PHILIP J. GODDARD;JEFFREY D. KLINGER;PRADEEP K. DHAL;W. HARRY MANDEVILLE
分类号 A61K31/28;A61K31/60;A61K33/12;A61K33/24;A61P11/12 主分类号 A61K31/28
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