发明名称 |
A MUTANT HUMAN HEPATITIS B VIRAL STRAIN AND USES THEREOF |
摘要 |
<p>An isolated strain of Hepatitis B virus designated Human Hepatitis B Virus Surface Antigen-"S'-133 Oon Strain (Methionine to Threonine) of Cell. Also, an isolated nucleic acid encoding a polypeptide which is a mutant major surface antigen of a strain of hepatitis B virus, such polypeptide having an amino acid sequence which differs from the amino acid sequence of a major surface antigen of a wild type hepatitis B virus in that the amino acid at position number 133 of such polypeptide is a threonine rather than methionine.</p> |
申请公布号 |
PL345573(A1) |
申请公布日期 |
2001.12.17 |
申请号 |
PL19980345573 |
申请日期 |
1998.06.19 |
申请人 |
GOVERNMENT OF REPUBLIC OF SINGAPORE |
发明人 |
OON CHONG JIN;LIM GEK KEOW;ZHAO YI;CHEN WEI NING |
分类号 |
G01N33/50;A61K38/00;A61K39/29;A61K45/00;A61P1/16;A61P31/20;A61P35/00;C07K14/02;C07K16/08;C12N7/00;C12N7/01;C12N15/01;C12N15/09;C12N15/51;C12P21/02;C12P21/08;C12Q1/68;G01N33/15;G01N33/576;G01N33/68;(IPC1-7):C12N15/51 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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