发明名称 |
Methods for producing chiral chromones, chromanes, amino substituted chromanes and intermediates therefor |
摘要 |
Disclosed are process steps and novel processes for producing chromane compositions enriched in at least one (2R or 2S) enantiomer, preferably chroman-2-yl carboxylic acid compounds and chroman-2-yl carboxylic acid esters which are intermediates for producing platelet aggregation inhibitors and/or are themselves potent platelet aggregation inhibitors. Further disclosed are enzymatic processes for resolving chiral intermediates or final products to provide desired enantiomers. |
申请公布号 |
AU6816201(A) |
申请公布日期 |
2001.12.17 |
申请号 |
AU20010068162 |
申请日期 |
2001.06.01 |
申请人 |
ELI LILLY AND COMPANY;COR THERAPEUTICS, INC. |
发明人 |
BARBARA BRIGGS;MARVIN HANSEN;JAMES KANTER;JOHN J. G. MULLINS;GERD RUHTER;UKO UDODONG;DANIEL VERRAL II;MILTON ZMIJEWSKI JR. |
分类号 |
A61K31/353;A61P7/02;C07D311/22;C07D311/24;C07D311/58;C07D311/74 |
主分类号 |
A61K31/353 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|