A cardiac phantom is provided for simulating a dynamic cardiac ventricle. The phantom comprises two concentrically-disposed, fluid-tight, flexible membranes defining a closed space between the walls of the membranes. A pump is operatively connected to the inner membrane for reciprocally delivering a volume of fluid to the inner membrane to inflate and deflate both membranes in simulating systole and diastole of a heart. A medium is disposed within the closed space defined between the walls of the membranes for maintaining a uniform distance between the walls of the membranes during inflation and deflation. The phantom is provided for evaluation of medical imaging systems. A method, computer system and a computer-readable medium are also provided for contolling the phantom.