METHODS FOR COUPLING BENZOYL COMPOUNDS AND AMINO SUBSTITUTED BICYCLIC DERIVATIVES AND ENANTIOMERICALLY PURE OR ENRICHED COMPOSITIONS MADE THEREFROM

摘要

Disclosed are processes for coupling amino substituted 2-chromanyl derivatives and benzoyl derivatives via an amide bond, and intermediates for producing platelet aggregation inhibitors and for producing potent platelet aggregation inhibitors. Also disclosed are processes for producing such compounds from chiral intermediates to provide desired enantiomers, and methods for using the compounds as platelet aggregation inhibitors.