PROCESS FOR THE SYNTHESIS OF (2R, 2-ALPHA-R, 3A)-2-[1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHOXY]-3-(4-FLUOROPHENYL)-1,4-OXAZINE
摘要
The present invention is concerned with novel processes for the preparation of (2R, 2-alpha-R, 3a)-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-3-(4-fluorophenyl)-1,4-oxazine. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.
申请公布号
WO0194324(A1)
申请公布日期
2001.12.13
申请号
WO2001US18042
申请日期
2001.06.04
申请人
MERCK & CO., INC.;BRANDS, KAREL, M., JOS;TSAY, FUH-RONG;CONRAD, KAREN, M.;ZHAO, MATTHEW, M.
发明人
BRANDS, KAREL, M., JOS;TSAY, FUH-RONG;CONRAD, KAREN, M.;ZHAO, MATTHEW, M.